Synergistic targeting of the PI3K/mTOR and MAPK/ERK pathways in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is an aggressive type of skin cancer, which is caused either by integration of the oncogenic Merkel cell polyomavirus (MCPyV) or by accumulation of UV-light induced mutations. Since the response to immune-checkpoint inhibitors is limited, new therapeutic agents need to be...

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Veröffentlicht in:	TUMOUR VIRUS RESEARCH 2022-12, Vol.14
Hauptverfasser:	Temblador, Arturo, Topalis, Dimitrios, Andrei, Graciela, Snoeck, Robert
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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