A Panel-Based Sequencing Analysis of Patients with Paget's Disease of Bone Suggests Enrichment of Rare Genetic Variation in regulators of NF-κB Signaling and Supports the Importance of the 7q33 Locus

Paget's disease of bone (PDB) is a common bone disorder characterized by focal lesions caused by increased bone turnover. Monogenic forms of PDB and PDB-related phenotypes as well as genome-wide association studies strongly support the involvement of genetic variation in components of the NF-κB...

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Veröffentlicht in:	CALCIFIED TISSUE INTERNATIONAL 2021-12, Vol.109 (6), p.656-665
Hauptverfasser:	De Ridder, Raphael, Vandeweyer, Geert, Boudin, Eveline, Hendrickx, Gretl, Huybrechts, Yentl, Cremers, Tycho Canter, Devogelaer, Jean-Pierre, Mortier, Geert, Fransen, Erik, Van Hul, Wim
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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