The role of the actin cytoskeleton in the regulation of the Hippo pathway
The Hippo pathway effectors YAP (Yes-associated protein) and TAZ (Transcriptional coactivator with PDZ-binding motif) promote organ growth and tumorigenesis and are indicated as promising targets for cancer therapy. This is because they are hyperactivated with high frequency in different types of hu...
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| Format: | Dissertation |
| Sprache: | eng |
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