Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is greatly limited by the lack of effective GMP-compliant systems for organoid expansion in culture. Here, we envisage that the use of extracel...

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Veröffentlicht in:NATURE COMMUNICATIONS 2019-12, Vol.10 (1)
Hauptverfasser: Giobbe, Giovanni Giuseppe, Crowley, Claire, Luni, Camilla, Campinoti, Sara, Khedr, Moustafa, Kretzschmar, Kai, De Santis, Martina Maria, Zambaiti, Elisa, Michielin, Federica, Meran, Laween, Hu, Qianjiang, van Son, Gijs, Urbani, Luca, Manfredi, Anna, Giomo, Monica, Eaton, Simon, Cacchiarelli, Davide, Li, Vivian S.W, Clevers, Hans, Bonfanti, Paola, Elvassore, Nicola, De Coppi, Paolo
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Sprache:eng
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