miR-15a-5p and miR-21-5p contribute to chemoresistance in cytogenetically normal acute myeloid leukaemia by targeting PDCD4, ARL2 and BTG2

Cytarabine and daunorubicin are old drugs commonly used in the treatment of acute myeloid leukaemia (AML). Refractory or relapsed disease because of chemotherapy resistance is a major issue. microRNAs (miRNAs) were incriminated in resistance. This study aimed to identify miRNAs involved in chemoresi...

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Veröffentlicht in:	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2020-12, Vol.25 (1), p.575-585
Hauptverfasser:	Vandewalle, Virginie, Essaghir, Ahmed, Bollaert, Emeline, Lenglez, Sandrine, Graux, Carlos, Schoemans, Helene, Saussoy, Pascale, Michaux, Lucienne, Valk, Peter J.M, Demoulin, Jean-Baptiste, Havelange, Violaine
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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