Intravenous pegylated liposomal prednisolone outperforms intramuscular methylprednisolone in treating rheumatoid arthritis flares: A randomized controlled clinical trial

Glucocorticoids (GCs) are potent anti-inflammatory drugs but their use is limited by systemic exposure leading to toxicity. Targeted GC delivery to sites of inflammation via encapsulation in long-circulating liposomes may improve the therapeutic index. We performed a randomized, double-blind, active...

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Veröffentlicht in:	JOURNAL OF CONTROLLED RELEASE 2022-01, Vol.341, p.548-554
Hauptverfasser:	Metselaar, Josbert M, Middelink, Leonie M, Wortel, Cornelis H, Bos, Reinhard, van Laar, Jacob M, Vonkeman, Harald E, Westhovens, Rene, Lammers, Twan, Yao, Siu-Long, Kothekar, Mudgal, Raut, Atul, Bijlsma, Johannes W.J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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