Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
Endocardial cushions are precursors of mature atrioventricular (AV) valves. Their formation is induced by signaling molecules originating from the AV myocardium, including bone morphogenetic proteins (BMPs). Here, we hypothesized that BMP signaling plays an important role in the AV myocardium during...
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Veröffentlicht in: | Circulation Research 2005-08, Vol.97 (3), p.219-26 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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