The microglial lysosomal system in Alzheimer's disease: Guardian against proteinopathy

Microglia, the brain-resident immune cells, play an essential role in the upkeep of brain homeostasis. They actively adapt into specific activation states based on cues from the microenvironment. One of these encompasses the activated response microglia (ARMs) phenotype. It arises along a healthy ag...

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Veröffentlicht in:AGEING RESEARCH REVIEWS 2021-11, Vol.71
Hauptverfasser: Van Acker, Zoe P, Perdok, Anika, Bretou, Marine, Annaert, Wim
Format: Artikel
Sprache:eng
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