An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive cellular responses occur is unclear. Here, we report development of 3-Dimensional culture analyses to separately quantify growth and invasion. We identify that alternate variants of I...

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Veröffentlicht in:	NATURE COMMUNICATIONS 2021-03, Vol.12 (1)
Hauptverfasser:	Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Roman-Fernandez, Alvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura C.A, Freckmann, Eva C, McGarry, Lynn, Morton, Jennifer P, Shanks, Emma, Leung, Hing Y, Markert, Elke, Ismail, Shehab, Zanivan, Sara, Blyth, Karen, Bryant, David M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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