Dynamic bistable switches enhance robustness and accuracy of cell cycle transitions

Bistability is a common mechanism to ensure robust and irreversible cell cycle transitions. Whenever biological parameters or external conditions change such that a threshold is crossed, the system abruptly switches between different cell cycle states. Experimental studies have uncovered mechanisms...

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Veröffentlicht in:	PLOS COMPUTATIONAL BIOLOGY 2021-01, Vol.17 (1)
Hauptverfasser:	Rombouts, Jan, Gelens, Lendert
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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