Contribution of the platelet activating factor signaling pathway to cerebral microcirculatory dysfunction during experimental sepsis by ExoU producing Pseudomonas aeruginosa

Intravital microscopy was used to assess the involvement of ExoU, a Pseudomonas aeruginosa cytotoxin with phospholipase A2 activity, in dysfunction of cerebral microcirculation during experimental pneumosepsis. Cortical vessels from mice intratracheally infected with low density of the ExoU-producin...

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Veröffentlicht in:PATHOGENS AND DISEASE 2015-10, Vol.73 (7)
Hauptverfasser: Plotkowski, Maria Cristina, Estato, Vanessa, Santos, Sabrina Alves, Alves da Silva, Mauricio Costa, Miranda, Aline Silva, de Miranda, Pedro Elias, Pinho, Vanessa, Tibirica, Eduardo, Morandi, Veronica, Teixeira, Mauro Martins, Vianna, Albanita, Saliba, Alessandra Mattos
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Sprache:eng
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