Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with anti-atrophic activity on skeletal muscle. Here, we show that not only lifelong overex...

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Veröffentlicht in:AGING-US 2020-07, Vol.12 (14), p.13939-13957
Hauptverfasser: Agosti, Emanuela, De Feudis, Marilisa, Angelino, Elia, Bellis, Roberta, Teixeira, Maraiza Alves, Zaggia, Ivan, Tamiso, Edoardo, Raiteri, Tommaso, Scircoli, Andrea, Ronzoni, Flavio L, Muscaritoli, Maurizio, Graziani, Andrea, Prodam, Flavia, Sampaolesi, Maurilio, Costelli, Paola, Ferraro, Elisabetta, ReanoL, Simone, Filigheddu, Nicoletta
Format: Artikel
Sprache:eng
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