Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice
Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with anti-atrophic activity on skeletal muscle. Here, we show that not only lifelong overex...
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Veröffentlicht in: | AGING-US 2020-07, Vol.12 (14), p.13939-13957 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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