Enzymatic Formation of an Artificial Base Pair Using a Modified Purine Nucleoside Triphosphate

The expansion of the genetic alphabet with additional, unnatural base pairs (UBPs) is an important and long-standing goal in synthetic biology. Nucleotides acting as ligands for the coordination of metal cations have advanced as promising candidates for such an expansion of the genetic alphabet. How...

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Veröffentlicht in:ACS CHEMICAL BIOLOGY 2020-11, Vol.15 (11), p.2872-2884
Hauptverfasser: Flamme, Marie, Rothlisberger, Pascal, Levi-Acobas, Fabienne, Chawla, Mohit, Oliva, Romina, Cavallo, Luigi, Gasser, Gilles, Marliere, Philippe, Herdewijn, Piet, Hollenstein, Marcel
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Sprache:eng
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