The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research

In this study, we report the results of a comprehensive phenotyping of the retina of the App NL-G-F mouse. We demonstrate that soluble Aβ accumulation is present in the retina of these mice early in life and progresses to Aβ plaque formation by midlife. This rising Aβ burden coincides with local mic...

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Veröffentlicht in:	bioRxiv 2020
Hauptverfasser:	Vandenabeele, Marjan, Veys, Lien, Lemmens, Sophie, Hadoux, Xavier, Gelders, Géraldine, Masin, Luca, Serneels, Lutgarde, Theunis, Jan, Saito, Takashi, Saido, Takaomi, Jayapala, Murali, De Boever, Patrick, De Strooper, Bart, Stalmans, Ingeborg, van Wijngaarden, Peter, Moons, Lieve, De Groef, Lies
Format:	Text Resource
Sprache:	eng
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