Local but not systemic administration of mesenchymal stromal cells ameliorates fibrogenesis in regenerating livers

Chronic liver injury leads to the accumulation of myofibroblasts resulting in increased collagen deposition and hepatic fibrogenesis. Treatments specifically targeting fibrogenesis are not yet available. Mesenchymal stromal cells (MSCs) are fibroblast-like stromal (stem) cells, which stimulate tissu...

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Veröffentlicht in:	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2019-09, Vol.23 (9), p.6238-6250
Hauptverfasser:	van der Helm, Danny, Barnhoorn, Marieke C, de Jonge-Muller, Eveline S.M, Molendijk, Ilse, Hawinkels, Luuk J.A.C, Coenraad, Minneke J, van Hoek, Bart, Verspaget, Hein W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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