Chimeric Antigen Receptor-T Cells for Targeting Solid Tumors: Current Challenges and Existing Strategies

Chimeric antigen receptor-T cells (CAR-Ts) are an exciting new cancer treatment modality exemplified by the recent regulatory approval of two CD19-targeted CAR-T therapies for certain B cell malignancies. However, this success in the hematological setting has yet to translate to a significant level...

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Veröffentlicht in:	BIODRUGS 2019-10, Vol.33 (5), p.515-537
Hauptverfasser:	Springuel, Lorraine, Lonez, Caroline, Alexandre, Bertrand, Van Cutsem, Eric, Machiels, Jean-Pascal H, Van Den Eynde, Marc, Prenen, Hans, Hendlisz, Alain, Shaza, Leila, Carrasco, Javier, Canon, Jean-Luc, Opyrchal, Mateusz, Odunsi, Kunle, Rottey, Sylvie, Gilham, David E, Flament, Anne, Lehmann, Frederic F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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