Cerebrospinal fluid levels of synaptic and neuronal integrity correlate with gray matter volume and amyloid load in the precuneus of cognitively intact older adults

The main pathophysiological alterations of Alzheimer's disease (AD) include loss of neuronal and synaptic integrity, amyloidogenic processing and neuroinflammation. Similar alterations can, however, also be observed in cognitively intact older subjects and may prelude the clinical manifestation...

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Veröffentlicht in:	J Neurochem 2019-02, Vol.149 (1), p.139-157
Hauptverfasser:	Schaeverbeke, Jolien, Gille, Benjamin, Adamczuk, Katarzyna, Vanderstichele, Hugo, Chassaing, Emeric, Bruffaerts, Rose, Neyens, Veerle, Stoops, Erik, Tournoy, Jos, Vandenberghe, Rik, Poesen, Koen
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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