Synthetic amyloids as a new generic platform for PET imaging. From infectious disease to cancer imaging
Experimental data demonstrated that amyloid-like aggregation of proteins is induced by short amyloidogenic Aggregation Prone Regions (APRs) within a protein sequence. These APRs are able to self-assemble into β-sheets, resulting in the typical cross-β structured backbone of amyloids. These amyloidog...
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Format: | Dissertation |
Sprache: | eng |
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