Polymorphism of indomethacin in semicrystalline dispersions: Formation, transformation and segregation

The crystallization of metastable crystal polymorphs in polymer matrices has been extensively reported in literature as a possible approach to enhance the solubility of poorly water-soluble drug compounds, yet no clarification of the mechanism of the polymorph formation has been proposed. The curren...

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Veröffentlicht in:	Molecular Pharmaceutics 2018-04, Vol.15 (3), p.1037-1051
Hauptverfasser:	Duong, Tu Van, Lüdeker, David, Van Bockstal, Pieter-Jan, De Beer, Thomas, Van Humbeeck, Jan, Van den Mooter, Guy
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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