Formulating monoclonal antibodies as powders for reconstitution at high concentration using spray drying: Models and pitfalls

In anticipation of non-invasive routes capable of delivering adequately high, systemic monoclonal antibody (mAb) concentrations, subcutaneous (SC) injection is arguably the most patient friendly alternative administration route available for this drug class. However, due to the limited volume that c...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European Journal of Pharmaceutics and Biopharmaceutics 2018-03, Vol.127, p.407-422
Hauptverfasser:	Batens, Maarten, Massant, Jan, Teodorescu, Bianca, Van den Mooter, Guy
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!