Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040
© 2017 Elsevier Ltd A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by...
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| Veröffentlicht in: | Tetrahedron 2017, Vol.73 (18), p.2633-2637 |
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| creator | Sonnenschein, Eva C Stierhof, Marc Goralczyk, Stephan Vabre, Floriane M Pellissier, Leonie Hanssen, Kine Ostnes de la Cruz, Mercedes Diaz, Caridad de Witte, Peter Copmans, Daniëlle Andersen, Jeanette Hammer Hansen, Espen Kristoffersen, Venke Tormo, Jose R Ebel, Rainer Milne, Bruce F Deng, Hai Gram, Lone Jaspars, Marcel Tabudravu, Jioji N |
| description | © 2017 Elsevier Ltd A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 μM, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity. |
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| ispartof | Tetrahedron, 2017, Vol.73 (18), p.2633-2637 |
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| source | Lirias (KU Leuven Association); ScienceDirect Journals (5 years ago - present) |
| title | Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040 |
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