TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells

Lipopolysaccharides (LPS), the major components of the wall of gram-negative bacteria, trigger powerful defensive responses in the airways via mechanisms thought to rely solely on the Toll-like receptor 4 (TLR4) immune pathway. Here we show that airway epithelial cells display an increase in intrace...

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Veröffentlicht in:	Nature Communications 2017-10, Vol.8 (1), p.1059
Hauptverfasser:	Aguiar Alpizar, Yeranddy, Boonen, Brett, Sanchez Linde, Alicia, Jung, Carole, López Requena, Alejandro, Naert, Robbe, Steelant, Brecht, Luyts, Katrien, Plata, Cristina, De Vooght, Vanessa, Vanoirbeek, Jeroen, Meseguer, Victor M, Voets, Thomas, Alvarez, Julio L, Hellings, Peter, Hoet, Peter, Nemery, Benoit, Valverde, Miguel A, Talavera Pérez, Karel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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