Pretransplant 4β-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation

The CYP3A metric 4β-hydroxycholesterol (4βOHC) has been shown to correlate with tacrolimus steady-state apparent oral clearance (CL/F). Recently, pretransplant 4βOHC was shown not to predict tacrolimus CL/F after transplantation in a cohort of renal recipients (n = 79). The goal of the current study...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	British Journal of Clinical Pharmacology 2017-11, Vol.83 (11), p.2406-2415
Hauptverfasser:	Vanhove, Thomas, Hasan, Mahmoud, Annaert, Pieter, Oswald, Stefan, Kuypers, Dirk
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!