Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression

Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in vitro-cultivated strains are highly aneuploid...

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Veröffentlicht in:	mBio 2017-05, Vol.8 (3)
Hauptverfasser:	Dumetz, F, Imamura, H, Sanders, M, Seblova, V, Myskova, J, Pescher, P, Vanaerschot, M, Meehan, C.J, Cuypers, B, De Muylder, G, Späth, G.F, Bussotti, G, Vermeesch, Joris, Berriman, M, Cotton, J.A, Volf, P, Dujardin, J.C, Domagalska, M.A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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