Replica exchange molecular dynamics study of the truncated amyloid beta (11-40) trimer in solution

Amyloid beta (Aβ) oligomers are neurotoxic compounds that destroy the brain of Alzheimer's disease patients. Recent studies indicated that the trimer is one of the most cytotoxic forms of low molecular weight Aβ oligomers. As there was limited information about the structure of the Aβ trimer, e...

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Veröffentlicht in:Physical Chemistry Chemical Physics 2017-01, Vol.19 (3), p.1909-1919
Hauptverfasser: Ngo, Son Tung, Huynh, Hung Minh, Truong, Duc Toan, Nguyen, Minh
Format: Artikel
Sprache:eng
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