Impact of chronic kidney disease on left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

Impact of chronic kidney disease on left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

BACKGROUND: Left atrial appendage occlusion (LAAO) using the Amplatzer cardiac plug (ACP) is a preventive treatment of atrial fibrillation related thromboembolism. AIM: To assess the safety and efficacy of LAAO in patients with chronic kidney disease (CKD). METHODS: Among the ACP multicentre registr...

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Veröffentlicht in:International Journal of Cardiology 2016, Vol.207, p.335-340
Hauptverfasser: Kefer, Joelle, Tzikas, Apostolos, Freixa, Xavier, Shakir, Samera, Gafoor, Sameer, Nielsen-Kudsk, Jens Erik, Berti, Sergio, Santoro, Gennaro, Aminian, Adel, Landmesser, Ulf, Nietlispach, Fabian, Ibrahim, Reda, Danna, Paolo Luciano, Benit, Edouard, Budts, Werner, Stammen, Francis, De Potter, Tom, Tichelbaecker, Tobias, Gloekler, Steffen, Kanagaratnam, Prapa, Costa, Marco, Cruz-Gonzalez, Ignacio, Sievert, Horst, Schillinger, Wolfgang, Park, Jai-Wun, Meier, Bernhard, Omran, Heyder
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Sprache:eng
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Zusammenfassung:BACKGROUND: Left atrial appendage occlusion (LAAO) using the Amplatzer cardiac plug (ACP) is a preventive treatment of atrial fibrillation related thromboembolism. AIM: To assess the safety and efficacy of LAAO in patients with chronic kidney disease (CKD). METHODS: Among the ACP multicentre registry, 1014 patients (75±8yrs) with available renal function were included. RESULTS: Patients with CKD (N=375, CHA2DS2-VASc: 4.9±1.5, HASBLED: 3.4±1.3) were at higher risk than patients without CKD (N=639, CHA2DS2-VASc: 4.2±1.6, HASBLED: 2.9±1.2; p
ISSN:0167-5273