Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Metastasis is the leading cause of death for cancer patients. This multi-stage process requires tumour cells to survive in the circulation, extravasate at distant sites, then proliferate; it involves contributions from both the tumour cell and tumour microenvironment ('host', which include...

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Veröffentlicht in:	Nature 2017, Vol.541 (7636), p.233-236
Hauptverfasser:	Weyden, Louise van der, Arends, Mark J, Campbell, Andrew D, Bald, Tobias, Wardle-Jones, Hannah, Griggs, Nicola, Velasco-Herrera, Martin Del Castillo, Tüting, Thomas, Sansom, Owen J, Karp, Natasha A, Clare, Simon, Gleeson, Diane, Ryder, Edward, Galli, Antonella, Tuck, Elizabeth, Cambridge, Emma L, Voet, Thierry, Macaulay, Iain C, Wong, Kim, Sanger Mouse Genetics Project, Spiegel, Sarah, Speak, Anneliese O, Adams, David J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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