Identification of drugs that restore primary cilium expression in cancer cells

The development of cancer is often accompanied by a loss of the primary cilium, a microtubule-based cellular protrusion that functions as a cellular antenna and that puts a break on cell proliferation. Hence, restoration of the primary cilium in cancer cells may represent a novel promising approach...

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Veröffentlicht in:Oncotarget 2016-03, Vol.7 (9), p.9975-92
Hauptverfasser: Khan, Niamat Ali, Willemarck, Nicolas, Talebi, Ali, Marchand, Arnaud, Binda, Maria Mercedes, Dehairs, Jonas, Rueda-Rincon, Natalia, Daniels, Veerle W, Bagadi, Muralidhararao, Raj, Deepak Balaji Thimiri Govinda, Vanderhoydonc, Frank, Munck, Sebastian, Chaltin, Patrick, Swinnen, Johan
Format: Artikel
Sprache:eng
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