An estimated glomerular filtration rate equation for the full age spectrum

Glomerular filtration rate (GFR) is accepted as the best indicator of kidney function and is commonly estimated from serum creatinine (SCr)-based equations. Separate equations have been developed for children (Schwartz equation), younger and middle-age adults [Chronic Kidney Disease Epidemiology Col...

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Veröffentlicht in:Nephrology, Dialysis, Transplantation Dialysis, Transplantation, 2016-05, Vol.31 (5), p.798-806
Hauptverfasser: Pottel, Hans, Hoste, Liesbeth, Dubourg, Laurence, Ebert, Natalie, Schaeffner, Elke, Eriksen, Bjørn Odvar, Melsom, Toralf, Lamb, Edmund J, Rule, Andrew D, Turner, Stephen T, Glassock, Richard J, De Souza, Vandréa, Selistre, Luciano, Mariat, Christophe, Martens, Frank, Delanaye, Pierre
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Sprache:eng
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Zusammenfassung:Glomerular filtration rate (GFR) is accepted as the best indicator of kidney function and is commonly estimated from serum creatinine (SCr)-based equations. Separate equations have been developed for children (Schwartz equation), younger and middle-age adults [Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation] and older adults [Berlin Initiative Study 1 (BIS1) equation], and these equations lack continuity with ageing. We developed and validated an equation for estimating the glomerular filtration rate that can be used across the full age spectrum (FAS).
ISSN:0931-0509