Shear-resistant Binding to Von Willebrand Factor Allows Staphylococcus Lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis
Staphylococcus lugdunensis (S. lugdunensis) is an emerging cause of endocarditis. To cause endovascular infections S. lugdunensis requires mechanisms to overcome shear stress. We investigated whether platelets and von Willebrand factor (VWF) mediate bacterial adhesion to the vessel wall and the card...
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Veröffentlicht in: | The Journal of Infectious Diseases 2016-04, Vol.213 (7), p.1148-56 |
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creator | Liesenborghs, Laurens Peetermans, Marijke Claes, Jorien Veloso, Rafael Vandenbriele, Christophe Criel, Maarten Lox, Marleen Peetermans, Willy Heilbronner, Simon de Groot, Philip G Vanassche, Thomas Hoylaerts, Marc Verhamme, Peter |
description | Staphylococcus lugdunensis (S. lugdunensis) is an emerging cause of endocarditis. To cause endovascular infections S. lugdunensis requires mechanisms to overcome shear stress. We investigated whether platelets and von Willebrand factor (VWF) mediate bacterial adhesion to the vessel wall and the cardiac valves under flow. |
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To cause endovascular infections S. lugdunensis requires mechanisms to overcome shear stress. We investigated whether platelets and von Willebrand factor (VWF) mediate bacterial adhesion to the vessel wall and the cardiac valves under flow.</abstract><pub>Published by the University of Chicago Press for the Infectious Diseases Society of America</pub></addata></record> |
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ispartof | The Journal of Infectious Diseases, 2016-04, Vol.213 (7), p.1148-56 |
issn | 0022-1899 |
language | eng |
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source | Lirias (KU Leuven Association); Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
title | Shear-resistant Binding to Von Willebrand Factor Allows Staphylococcus Lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis |
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