Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

BACKGROUND: Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in the innate immune system. Considering the central role of inflammasome signaling in innate immunity, we studied inflammasome components in IBD mucosa. METHODS: Expression o...

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Veröffentlicht in:	Inflammatory Bowel Diseases 2015, Vol.21 (11), p.2673-2682
Hauptverfasser:	Vanhove, Wiebe, Peeters, Paul, Staelens, Dominiek, Schraenen, Anica, Van der Goten, Jan, Cleynen, Isabelle, De Schepper, Seppe, Van Lommel, Leentje, Reynaert, Niki L, Schuit, Frans, Van Assche, Gert, Ferrante, Marc, De Hertogh, Gert, Wouters, Emiel F.M, Rutgeerts, Paul, Vermeire, Séverine, Nys, Kris, Arijs, Ingrid
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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