Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4

The chemokine receptor CXCR4 acts as a key cell surface receptor in HIV infections, multiple forms of cancer, and various other pathologies, such as rheumatoid arthritis and asthma. Macrocyclic polyamines and their metal complexes are known to exert anti-HIV activity, many acting as HIV entry inhibi...

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Veröffentlicht in:	Organic & Biomolecular Chemistry 2015-11, Vol.13 (42), p.10517-26
Hauptverfasser:	Hamal, Sunil, D'huys, Thomas, Rowley, William F, Vermeire, Kurt, Aquaro, Stefano, Frost, Brian J, Schols, Dominique, Bell, Thomas W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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