Reduced cortisol metabolism during critical illness
Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may be due to reduced cortisol metabolism.
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| Veröffentlicht in: | New England Journal of Medicine 2013-04, Vol.368 (16), p.1477-1488 |
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| container_end_page | 1488 |
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| container_issue | 16 |
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| container_title | New England Journal of Medicine |
| container_volume | 368 |
| creator | Boonen, Eva Vervenne, Hilke Meersseman, Philippe Andrew, Ruth Mortier, Leentje Declercq, Peter Vanwijngaerden, Yoo-Mee Spriet, Isabel Wouters, Pieter Vander Perre, Sarah Langouche, Lies Vanhorebeek, Ilse Walker, Brian R Van den Berghe, Greet |
| description | Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may be due to reduced cortisol metabolism. |
| format | Article |
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| identifier | ISSN: 0028-4793 |
| ispartof | New England Journal of Medicine, 2013-04, Vol.368 (16), p.1477-1488 |
| issn | 0028-4793 |
| language | eng |
| recordid | cdi_kuleuven_dspace_123456789_399064 |
| source | Lirias (KU Leuven Association); EZB-FREE-00999 freely available EZB journals; New England Journal of Medicine Current |
| title | Reduced cortisol metabolism during critical illness |
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