The Life History of 21 Breast Cancers

Cancer evolves dynamically as clonal expansions supersede one another driven by shifting selective pressures, mutational processes, and disrupted cancer genes. These processes mark the genome, such that a cancer's life history is encrypted in the somatic mutations present. We developed algorith...

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Veröffentlicht in:	CELL 2012-05, Vol.149 (5)
Hauptverfasser:	Nik-Zainal, Serena, Van Loo, Peter, Wedge, David C, Alexandrov, Ludmil B, Greenman, Christopher D, Lau, King Wai, Raine, Keiran, Jones, David, Marshall, John, Ramakrishna, Manasa, Shlien, Adam, Cooke, Susanna L, Hinton, Jonathan, Menzies, Andrew, Stebbings, Lucy A, Leroy, Catherine, Jia, Mingming, Rance, Richard, Mudie, Laura J, Gamble, Stephen J, Stephens, Philip J, McLaren, Stuart, Tarpey, Patrick S, Papaemmanuil, Elli, Davies, Helen R, Varela, Ignacio, McBride, David J, Bignell, Graham R, Leung, Kenric, Butler, Adam P, Teague, Jon W, Martin, Sancha, Joensson, Goran, Mariani, Odette, Boyault, Sandrine, Miron, Penelope, Fatima, Aquila, Langerod, Anita, Aparicio, Samuel A.J.R, Tutt, Andrew, Sieuwerts, Anieta M, Borg, Ake, Thomas, Gilles, Salomon, Anne Vincent, Richardson, Andrea L, Borresen-Dale, Anne-Lise, Futreal, P. Andrew, Stratton, Michael R, Campbell, Peter J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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