Efficient synthesis of exomethylene- and keto-exomethylene-d-glucopyranosyl nucleoside analogs as potential cytotoxic agents

A novel series of exomethylene- and keto-exomethylene-d-glucopyranonucleosides with thymine, uracil, and 5-fluorouracil as heterocyclic bases have been designed and synthesized. Wittig condensation of the 3-keto glucoside 1 gave the corresponding 1,2:5,6-di-O-isopropylidene-3-deoxy-3-methylene-d-glu...

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Veröffentlicht in:	Carbohydrate Research 2011-02, Vol.346 (2), p.328-33
Hauptverfasser:	Tzioumaki, Niki, Tsoukala, Evangelia, Manta, Stella, Kiritsis, Christos, Balzarini, Jan, Komiotis, Dimitri
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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