Microvirin, a novel {alpha}(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of Cyanovirin-N but a much higher safety profile

Microvirin (MVN), a recently isolated lectin from the cyanobacterium Microcystis aeruginosa PCC7806, shares 33% identity with the potent anti-human immunodeficiency virus (HIV) protein cyanovirin-N (CV-N) isolated from Nostoc ellipsosporum, and both lectins bind to similar carbohydrate structures. M...

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Veröffentlicht in:	Journal of Biological Chemistry 2010-08, Vol.285 (32), p.24845-24854
Hauptverfasser:	Huskens, Dana, Férir, Geoffrey, Vermeire, Kurt, Kehr, Jan-Christoph, Balzarini, Jan, Dittmann, Elke, Schols, Dominique
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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