Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials

PURPOSE: Dermatofibrosarcoma protuberans (DFSP) is a dermal sarcoma typically carrying a translocation between chromosomes 17 and 22 that generates functional platelet-derived growth factor B (PDGFB). PATIENTS AND METHODS: Two distinct phase II trials of imatinib (400 to 800 mg daily) in patients wi...

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Veröffentlicht in:	Journal of Clinical Oncology 2010-03, Vol.28 (10), p.1772-1779
Hauptverfasser:	Rutkowski, Piotr, Van Glabbeke, Martine, Rankin, Cathryn J, Ruka, Wlodzimierz, Rubin, Brian P, Debiec-Rychter, Maria, Lazar, Alexander, Gelderblom, Hans, Sciot, Raphael, Lopez-Terrada, Dolores, Hohenberger, Peter, Van Oosterom, Allan, Schuetze, Scott M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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