Nicotine activates the chemosensory cation channel TRPA1

Topical application of nicotine, as used in nicotine replacement therapies, causes irritation of the mucosa and skin. This reaction has been attributed to activation of nicotinic acetylcholine receptors (nAChRs) in chemosensory neurons. In contrast with this view, we found that the chemosensory cati...

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Veröffentlicht in:	Nature Neuroscience 2009-10, Vol.12 (10), p.1293-1299
Hauptverfasser:	Talavera Pérez, Karel, Gees, Maarten, Karashima, Yuji, Meseguer, Víctor M, Vanoirbeek, Jeroen, Damann, Nils, Everaerts, Wouter, Benoit, Melissa, Janssens, Annelies, Vennekens, Rudi, Viana, Félix, Nemery, Benoit, Nilius, Bernd, Voets, Thomas
Format:	Artikel
Sprache:	eng
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