Biological, pharmaceutical, and analytical considerations with respect to the transport media used in the absorption screening system, Caco-2
During the evaluation and selection of drug candidates, the Caco-2 cell culture system is commonly used for the determination of intestinal transport characteristics and to anticipate permeability limited drug absorption. Although classic HBSS-like buffered salt solutions are commonly used to perfor...
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| Veröffentlicht in: | Journal of pharmaceutical sciences 2003-08, Vol.92 (8), p.1545-58 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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