Single nucleotide polymorphism-based analysis of the genetic structure of the Min pig conserved population

Single nucleotide polymorphism-based analysis of the genetic structure of the Min pig conserved population

Objective: The study aims to uncover the genetic diversity and unique genetic structure of the Min pig conserved population, divide the nucleus conservation population, and construct the molecular pedigree. Methods: We used KPS Porcine Breeding Chip v1 50K for SNP detection of 94 samples (31♂, 63♀)...

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Veröffentlicht in:Animal bioscience 2022, Vol.35 (12), p.1839-1849
Hauptverfasser: Meng, Fanbing, Cai, Jiancheng, Wang, Chunan, Fu, Dechang, Di, Shengwei, Wang, Xibiao, Chang, Yang, Xu, Chunzhu
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container_end_page 1849
container_issue 12
container_start_page 1839
container_title Animal bioscience
container_volume 35
creator Meng, Fanbing
Cai, Jiancheng
Wang, Chunan
Fu, Dechang
Di, Shengwei
Wang, Xibiao
Chang, Yang
Xu, Chunzhu
description Objective: The study aims to uncover the genetic diversity and unique genetic structure of the Min pig conserved population, divide the nucleus conservation population, and construct the molecular pedigree. Methods: We used KPS Porcine Breeding Chip v1 50K for SNP detection of 94 samples (31♂, 63♀) in the Min pig conserved population from Lanxi breeding Farm. Results: The polymorphic marker ratio (PN), the observed heterozygosity (Ho), and the expected heterozygosity (He) were 0.663, 0.335, and 0.330, respectively. The pedigree-based inbreeding coefficients (FPED) was significantly different from those estimated from runs of homozygosity (FROH) and single nucleotide polymorphism (FSNP) based on genome. The Pearson correlation coefficient between FROH and FSNP was significant (p
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Methods: We used KPS Porcine Breeding Chip v1 50K for SNP detection of 94 samples (31♂, 63♀) in the Min pig conserved population from Lanxi breeding Farm. Results: The polymorphic marker ratio (PN), the observed heterozygosity (Ho), and the expected heterozygosity (He) were 0.663, 0.335, and 0.330, respectively. The pedigree-based inbreeding coefficients (FPED) was significantly different from those estimated from runs of homozygosity (FROH) and single nucleotide polymorphism (FSNP) based on genome. The Pearson correlation coefficient between FROH and FSNP was significant (p&lt;0.05). The effective population content (Ne) showed a continuously decreasing trend. The rate of decline was the slowest from 200 to 50 generations ago (r = 0.95), then accelerated slightly from 50 to 5 generations ago (1.40&lt;r&lt;1.50) and increased significantly in the last 5 generations (r = 2.6). According to the composition of Chinese lineage, we separated the nucleus conservation population (81 individuals) and the candidate conservation population (13 individuals) of Min pig, then the nucleus conservation population of Min pig was divided into 9 families by genomic information matrix. Conclusion: Our study indicated that the genetic diversity of the Min pig conserved population was inadequate. Due to the introgression of European commercial pig breeds and the unscientific breeding process, it is necessary to construct the molecular pedigree of the nucleus conservation population for the Min pig.</description><identifier>ISSN: 2765-0189</identifier><identifier>EISSN: 2765-0235</identifier><language>kor</language><ispartof>Animal bioscience, 2022, Vol.35 (12), p.1839-1849</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,4014</link.rule.ids></links><search><creatorcontrib>Meng, Fanbing</creatorcontrib><creatorcontrib>Cai, Jiancheng</creatorcontrib><creatorcontrib>Wang, Chunan</creatorcontrib><creatorcontrib>Fu, Dechang</creatorcontrib><creatorcontrib>Di, Shengwei</creatorcontrib><creatorcontrib>Wang, Xibiao</creatorcontrib><creatorcontrib>Chang, Yang</creatorcontrib><creatorcontrib>Xu, Chunzhu</creatorcontrib><title>Single nucleotide polymorphism-based analysis of the genetic structure of the Min pig conserved population</title><title>Animal bioscience</title><addtitle>Animal bioscience</addtitle><description>Objective: The study aims to uncover the genetic diversity and unique genetic structure of the Min pig conserved population, divide the nucleus conservation population, and construct the molecular pedigree. 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According to the composition of Chinese lineage, we separated the nucleus conservation population (81 individuals) and the candidate conservation population (13 individuals) of Min pig, then the nucleus conservation population of Min pig was divided into 9 families by genomic information matrix. Conclusion: Our study indicated that the genetic diversity of the Min pig conserved population was inadequate. 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title Single nucleotide polymorphism-based analysis of the genetic structure of the Min pig conserved population
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