Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma
Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute...
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| Veröffentlicht in: | Clinical endoscopy 2022-03, Vol.55 (2), p.287-291 |
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| creator | Yujin Lee Jaekwang Lee Hyunsoo Kim Changkeun Park Jaekwon Jung Daejin Kim Yun Jin Chung Hanjun Ryu |
| description | Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis. Clin Endosc 2022;55:287-291 |
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We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis. 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We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis. Clin Endosc 2022;55:287-291</description><subject>Acute liver failure</subject><subject>Hepatic infiltration</subject><subject>Liver biopsy</subject><subject>Malignant melanoma</subject><issn>2234-2400</issn><issn>2234-2443</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNo9j71qwzAURkVpoSHJE3TR0tEg3yv_jSY0TRqHDM1urpXrIuLIwVIKffsKWjJ9Zzgc-B7EDAB1Alrj452VehZL722ntC4Q01zNxK42t8Cysd88yTXZ4Tax_GQzuhNNPzKMcsNXCtbIrevtEKbIo5NjL_c02C9HLsg9D-TGCy3EU0-D5-X_zsVx_XZcbZLm8L5d1U1yzhQmqdZZlqLKoGQojCYwOYMBKgwxs1FpWTGZrqK0RKyiiJ1hoztEpXsocC5e_7Jn64Nt3ckP7Ue9O4ACgCw-hipXFUbv5e759jrZS3zUxmKZloC_GvRR6g</recordid><startdate>20220330</startdate><enddate>20220330</enddate><creator>Yujin Lee</creator><creator>Jaekwang Lee</creator><creator>Hyunsoo Kim</creator><creator>Changkeun Park</creator><creator>Jaekwon Jung</creator><creator>Daejin Kim</creator><creator>Yun Jin Chung</creator><creator>Hanjun Ryu</creator><general>대한소화기내시경학회</general><scope>HZB</scope><scope>Q5X</scope><scope>JDI</scope></search><sort><creationdate>20220330</creationdate><title>Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma</title><author>Yujin Lee ; Jaekwang Lee ; Hyunsoo Kim ; Changkeun Park ; Jaekwon Jung ; Daejin Kim ; Yun Jin Chung ; Hanjun Ryu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k503-14455130528e27c4a2c6e2c2a7caeeec0189eacb9a183393053bcec4b3304f273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2022</creationdate><topic>Acute liver failure</topic><topic>Hepatic infiltration</topic><topic>Liver biopsy</topic><topic>Malignant melanoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yujin Lee</creatorcontrib><creatorcontrib>Jaekwang Lee</creatorcontrib><creatorcontrib>Hyunsoo Kim</creatorcontrib><creatorcontrib>Changkeun Park</creatorcontrib><creatorcontrib>Jaekwon Jung</creatorcontrib><creatorcontrib>Daejin Kim</creatorcontrib><creatorcontrib>Yun Jin Chung</creatorcontrib><creatorcontrib>Hanjun Ryu</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><collection>KoreaScience</collection><jtitle>Clinical endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yujin Lee</au><au>Jaekwang Lee</au><au>Hyunsoo Kim</au><au>Changkeun Park</au><au>Jaekwon Jung</au><au>Daejin Kim</au><au>Yun Jin Chung</au><au>Hanjun Ryu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma</atitle><jtitle>Clinical endoscopy</jtitle><addtitle>Clinical Endoscopy</addtitle><date>2022-03-30</date><risdate>2022</risdate><volume>55</volume><issue>2</issue><spage>287</spage><epage>291</epage><pages>287-291</pages><issn>2234-2400</issn><eissn>2234-2443</eissn><abstract>Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis. 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| ispartof | Clinical endoscopy, 2022-03, Vol.55 (2), p.287-291 |
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| language | kor |
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| source | KoreaMed Synapse; DOAJ Directory of Open Access Journals; PubMed Central Open Access; KoreaMed Open Access; PubMed Central |
| subjects | Acute liver failure Hepatic infiltration Liver biopsy Malignant melanoma |
| title | Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma |
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