Reactive microglia and mitochondrial unfolded protein response following ventriculomegaly and behavior defects in kaolin-induced hydrocephalus

Ventriculomegaly induced by the abnormal accumulation of cerebrospinal fluid (CSF) leads to hydrocephalus, which is accompanied by neuroinflammation and mitochondrial oxidative stress. The mitochondrial stress activates mitochondrial unfolded protein response (UPRmt), which is essential for mitochon...

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Veröffentlicht in:BMB reports 2022-04, Vol.55 (4), p.181-186
Hauptverfasser: Zhu, Jiebo, Lee, Min Joung, Chang, Hee Jin, Ju, Xianshu, Cui, Jianchen, Lee, Yu Lim, Go, Dahyun, Chung, Woosuk, Oh, Eungseok, Heo, Jun Young
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