Hemistepsin A inhibits T0901317-induced lipogenesis in the liver

Hemistepsin A (HsA) is a guaianolide sesquiterpene lactone that inhibits hepatitis and liver fibrosis. We evaluated the effects of HsA on liver X receptor (LXR)-mediated hepatic lipogenesis in vitro and in vivo. Up to 10 μM, HsA did not affect the viability of HepG2 and Huh7 cells. Pretreatment with...

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Veröffentlicht in:	BMB reports 2021-02, Vol.54 (2), p.106-111
Hauptverfasser:	Kim, Jae Kwang, Cho, Il Je, Kim, Eun Ok, Lee, Dae Geon, Jung, Dae Hwa, Ki, Sung Hwan, Ku, Sae Kwang, Kim, Sang Chan
Format:	Artikel
Sprache:	kor
Schlagworte:	Fatty liver Hemistepsin A HsA Liver X receptor Sterol regulatory element-binding protein-1c T0901317
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