Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses

Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally, and the WHO has declared this outbreak a pandemic. Vaccines are an effective way to prevent the rapid spread of COVID-19. Furthermore, the immune response...

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Veröffentlicht in:Journal of microbiology and biotechnology 2020-08, Vol.30 (8), p.1109-1115
Hauptverfasser: Kim, Kyun-Do, Hwang, Insu, Ku, Keun Bon, Lee, Sumin, Kim, Seong-Jun, Kim, Chonsaeng
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Coronavirus
COVID-19
immune response
SARS-CoV-2
vaccine
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container_title Journal of microbiology and biotechnology
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creator Kim, Kyun-Do
Hwang, Insu
Ku, Keun Bon
Lee, Sumin
Kim, Seong-Jun
Kim, Chonsaeng
description The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally, and the WHO has declared this outbreak a pandemic. Vaccines are an effective way to prevent the rapid spread of COVID-19. Furthermore, the immune response against SARS-CoV-2 infection needs to be understood for the development of an efficient and safe vaccine. Here, we review the current understanding of vaccine targets and the status of vaccine development for COVID-19. We also describe host immune responses to highly pathogenic human coronaviruses in terms of innate and adaptive immunities.
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Coronavirus
COVID-19
immune response
SARS-CoV-2
vaccine
title Progress and Challenges in the Development of COVID-19 Vaccines and Current Understanding of SARS-CoV-2- Specific Immune Responses
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