15d-PGJ 2 inhibits NF-κB and AP-1-mediated MMP-9 expression and invasion of breast cancer cell by means of a heme oxygenase-1-dependent mechanism

Activation of peroxisome proliferator-activated receptor γ(PPARγ) serves as a key factor in the proliferation and invasion of breast cancer cells and is a potential therapeutic target for breast cancer. However, the mechanisms underlying this effect remain largely unknown. Heme oxygenase-1 (HO-1) is...

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Veröffentlicht in:BMB reports 2020-04, Vol.53 (4), p.212-217
Hauptverfasser: Jang, Hye-Yeon, Hong, On-Yu, Youn, Hyun Jo, Kim, Min-Gul, Kim, Cheorl-Ho, Jung, Sung Hoo, Kim, Jong-Suk
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