Analogs of Periplanetasin-4 Exhibit Deteriorated Membrane-Targeted Action

Periplanetasin-4 is an antimicrobial peptide with 13 amino acids identified in cockroaches. It has been reported to induce fungal cell death by apoptosis and membrane-targeted action. Analogs were designed by substituting arginine residues to modify the electrostatic and hydrophobic interactions acc...

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Veröffentlicht in:Journal of microbiology and biotechnology 2020-03, Vol.30 (3), p.382-390
Hauptverfasser: Lee, Heejeong, Hwang, Jae Sam, Lee, Dong Gun
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Sprache:kor
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