Pharmacological Analysis of Vorinostat Analogues as Potential Anti-tumor Agents Targeting Human Histone Deacetylases: an Epigenetic Treatment Stratagem for Cancers

Alteration of the acetylation status of chromatin and other non-histone proteins by HDAC inhibitors has evolved as an excellent epigenetic strategy in treatment of cancers. The present study was sought to identify compounds with positive pharmacological profiles targeting HDAC1. Analogues of Vorinos...

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Veröffentlicht in:Asian Pacific journal of cancer prevention : APJCP 2016, Vol.17 (3), p.1571-1576
Hauptverfasser: Praseetha, Sugathan, Bandaru, Srinivas, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai
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Sprache:kor
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