A New Protein Factor in the Product Formation of Non-Reducing Fungal Polyketide Synthase with a C-Terminus Reductive Domain

Azaphilone polyketides are synthesized by iterative non-reducing fungal polyketide synthases (NR-fPKSs) with a C-terminus reductive domain (-R). Several azaphilone biosynthetic gene clusters contain a putative serine hydrolase gene; the Monascus azaphilone pigment (MAzP) gene cluster harbors mppD. T...

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Veröffentlicht in:	Journal of microbiology and biotechnology 2015-10, Vol.25 (10), p.1648-1652
Hauptverfasser:	Balakrishnan, Bijinu, Chandran, Ramya, Park, Si-Hyung, Kwon, Hyung-Jin
Format:	Artikel
Sprache:	kor
Schlagworte:	azaphilone polyketide Monascus pigment MppD non-reducing fungal polyketide synthase Ser/Asp/His catalytic triad
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