Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital

Background: Potentially harmful unplanned extubation (UE) may occur in patients on mechanical ventilation (MV) in an intensive care unit (ICU) setting. This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Met...

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Veröffentlicht in:Tuberculosis and respiratory diseases 2015-10, Vol.78 (4), p.336-340
Hauptverfasser: Lee, Tae Won, Hong, Jeong Woo, Yoo, Jung-Wan, Ju, Sunmi, Lee, Seung Hun, Lee, Seung Jun, Cho, Yu Ji, Jeong, Yi Yeong, Lee, Jong Deog, Kim, Ho Cheol
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container_end_page 340
container_issue 4
container_start_page 336
container_title Tuberculosis and respiratory diseases
container_volume 78
creator Lee, Tae Won
Hong, Jeong Woo
Yoo, Jung-Wan
Ju, Sunmi
Lee, Seung Hun
Lee, Seung Jun
Cho, Yu Ji
Jeong, Yi Yeong
Lee, Jong Deog
Kim, Ho Cheol
description Background: Potentially harmful unplanned extubation (UE) may occur in patients on mechanical ventilation (MV) in an intensive care unit (ICU) setting. This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Methods: We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results: A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%) experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patients who required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation (19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p
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This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Methods: We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results: A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%) experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patients who required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation (19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p&lt;0.05). In addition, mortality rate was significantly higher among patients requiring reintubation than among those not requiring reintubation (54.5% vs. 5.9%; p=0.007). These two groups of patients exhibited no significant differences, within 2 hours after UE, in the fraction of inspired oxygen, blood pressure, heart rate, respiratory rate, and pH. Conclusion: Although reintubation may not always be required in patients with UE, it is associated with a poor outcome after UE.</description><identifier>ISSN: 1738-3536</identifier><identifier>EISSN: 2005-6184</identifier><language>kor</language><publisher>대한결핵 및 호흡기학회</publisher><subject>Airway Extubation ; Artificial Intensive Care Units ; Respiration</subject><ispartof>Tuberculosis and respiratory diseases, 2015-10, Vol.78 (4), p.336-340</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,778,782,883</link.rule.ids></links><search><creatorcontrib>Lee, Tae Won</creatorcontrib><creatorcontrib>Hong, Jeong Woo</creatorcontrib><creatorcontrib>Yoo, Jung-Wan</creatorcontrib><creatorcontrib>Ju, Sunmi</creatorcontrib><creatorcontrib>Lee, Seung Hun</creatorcontrib><creatorcontrib>Lee, Seung Jun</creatorcontrib><creatorcontrib>Cho, Yu Ji</creatorcontrib><creatorcontrib>Jeong, Yi Yeong</creatorcontrib><creatorcontrib>Lee, Jong Deog</creatorcontrib><creatorcontrib>Kim, Ho Cheol</creatorcontrib><title>Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital</title><title>Tuberculosis and respiratory diseases</title><addtitle>Tuberculosis and Respiratory Diseases</addtitle><description>Background: Potentially harmful unplanned extubation (UE) may occur in patients on mechanical ventilation (MV) in an intensive care unit (ICU) setting. This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Methods: We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results: A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%) experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patients who required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation (19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p&lt;0.05). In addition, mortality rate was significantly higher among patients requiring reintubation than among those not requiring reintubation (54.5% vs. 5.9%; p=0.007). These two groups of patients exhibited no significant differences, within 2 hours after UE, in the fraction of inspired oxygen, blood pressure, heart rate, respiratory rate, and pH. 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This study aimed to evaluate the clinical characteristics of UE and its impact on clinical outcomes in patients with MV in a medical ICU (MICU). Methods: We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results: A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%) experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patients who required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation (19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p&lt;0.05). In addition, mortality rate was significantly higher among patients requiring reintubation than among those not requiring reintubation (54.5% vs. 5.9%; p=0.007). These two groups of patients exhibited no significant differences, within 2 hours after UE, in the fraction of inspired oxygen, blood pressure, heart rate, respiratory rate, and pH. Conclusion: Although reintubation may not always be required in patients with UE, it is associated with a poor outcome after UE.</abstract><pub>대한결핵 및 호흡기학회</pub><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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source KoreaMed Synapse; DOAJ Directory of Open Access Journals; PubMed Central Open Access; KoreaMed Open Access; PubMed Central
subjects Airway Extubation
Artificial Intensive Care Units
Respiration
title Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital
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