The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis

Hypoxia-inducible factor (HIF) is a key regulator of tumor growth and angiogenesis. Recent studies have shown that, BIX01294, a G9a histone methyltransferase (HMT)-specific inhibitor, induces apoptosis and inhibits the proliferation, migration, and invasion of cancer cells. However, not many studies...

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Veröffentlicht in:	Molecules and cells 2015, Vol.38 (6), p.528-534
Hauptverfasser:	Oh, Su Young, Seok, Ji Yoon, Choi, Young Sun, Lee, Sung Hee, Bae, Jong-Sup, Lee, You Mie
Format:	Artikel
Sprache:	kor
Online-Zugang:	Volltext
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